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Expression Lines

Argireline Smoothing Cream

Expression lines, softened without needles.

Acetyl hexapeptide-3 that relaxes expression lines. The topical alternative to invasive procedures.

$62.00 30ml / 1 fl oz
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Free shipping on orders over $80 · Formulated in small batches

The Argireline Smoothing Cream combines acetyl hexapeptide-3 (Argireline) with leuphasyl and Snap-8 — a trio of peptides that work synergistically to reduce muscle contraction intensity. The result is a visible softening of expression lines at the forehead, around the eyes, and at the corners of the mouth, without the frozen appearance or recovery time of injectables.

Peptide Concentration Primary Function
Argireline 10% SNARE complex inhibition, reduced muscle contraction
Snap-8 4% Enhanced expression line reduction
Leuphasyl 4% Synergistic with Argireline, enkephalin pathway
  • Argireline (Acetyl Hexapeptide-3)
  • Leuphasyl (Pentapeptide-18)
  • Snap-8 (Acetyl Octapeptide-3)
  • Shea Butter
  • Jojoba Esters
  • Bisabolol
  • Tocopherol (Vitamin E)

Argireline works by mimicking the N-terminal end of SNAP-25, one of the proteins in the SNARE complex that muscles need to contract. By competing with SNAP-25, Argireline partially inhibits the neurotransmitter release that triggers facial muscle contraction. The effect is subtler than botulinum toxin — targeted at the skin surface rather than blocking nerve signals entirely — but cumulative with consistent use. At 10%, our formulation reaches the concentration shown in studies to produce statistically significant reductions in wrinkle depth.

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Each formula targets a distinct biological pathway. They're designed to complement one another.

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