Clinically-backed wrinkle reduction, undiluted.
Clinically-backed palmitoyl pentapeptide for visible reduction in fine lines and wrinkles.
Free shipping on orders over $80 · Formulated in small batches
The Matrixyl Concentrate delivers two generations of Matrixyl peptides — Matrixyl 3000 (palmitoyl tripeptide-1 + palmitoyl tetrapeptide-7) and Matrixyl Synthe6 (palmitoyl tripeptide-38) — at concentrations shown to produce measurable anti-wrinkle results in clinical studies. These peptides signal dermal fibroblasts to upregulate production of collagen I, III, IV, fibronectin, and hyaluronic acid.
Every peptide listed. Every concentration disclosed. No proprietary blends hiding ineffective doses.
INCI-style full disclosure. No hidden ingredients, no "fragrance" catch-all.
Matrixyl was first introduced by Sederma in 2000 and quickly became the most clinically-studied cosmetic peptide. What makes Matrixyl different from other anti-aging actives is its mechanism: rather than exfoliating or damaging skin to trigger repair, it directly mimics the signal peptides your skin uses to initiate collagen production. It works with skin biology, not against it. Matrixyl Synthe6 (the second generation) targets six components of the dermal matrix simultaneously — an advance that clinical data suggests doubles its wrinkle-reducing efficacy versus first-generation Matrixyl.
Each formula targets a distinct biological pathway. They're designed to complement one another.
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